Disease associated polymorphism in the ctla-4 locus

Details Disease associated polymorphism in the ctla-4 locus Disease associated polymorphism in the ctla-4 locus

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2441813

The present invention relates to the identification of Single Nucleotide Polymorphisms (SNPs) and haplotypes in the CTLA-4 locus and their association with a predisposition, susceptibility or resistance to autoimmune disease such as Graves Disease (GD) or Type 1 Diabetes Mellitus.(T1DM)

L'invention concerne l'identification de polymorphismes de nucléotide simple et d'haplotypes dans le locus CTLA-4 et leur association à une prédisposition, une susceptibilité ou une résistance à une maladie auto-immune, notamment de goitre exophtalmique ou de diabète sucré de type 1.

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