C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/55 (2006.01) A61K 38/46 (2006.01) C07K 16/40 (2006.01) C12N 9/16 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2265449
The present invention provides human protein tyrosine phosphatases (HPTP) and polynucleotides which identify and encode HPTP. The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HPTP and for a method of producing HPTP. The invention also provides for pharmaceutical compositions comprising HPTP or antagonists of HPTP, and antibodies which specifically bind HPTP. Additionally, the invention provides antisense molecules to HPTP for treatment or prevention of diseases associated with abnormal expression of HPTP.
Cette invention concerne de nouvelles tyrosine phosphatases protéiques humaines (TPPH) et des polynucléotides qui identifient et codent les TPPH; des vecteurs d'expression produits par génie génétique et des cellules hôtes comprenant les séquences nucléotidiques qui codent les TPPH ainsi qu'un procédé de production de TPPH; des compositions pharmaceutiques comprenant TPPH ou des antagonistes de TPPH, ainsi que des anticorps qui se lient spécifiquement à TPPH; et des molécules antisens des TPPH qui servent dans le traitement ou la prévention de maladies associées à l'expression anormale de TPPH.
Incyte Genomics Inc.
Incyte Pharmaceuticals Inc.
Smart & Biggar
LandOfFree
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