A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61P 11/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) C12N 15/113 (2010.01) C40B 30/00 (2006.01)
Patent
CA 2714410
The present invention encompasses miRNA profiles and type-I IFN/IFN.alpha.- induced PD marker profiles in inflam-matory or autoimmune disorders, such as myositis. The profiles may also be used in, for example, methods of treating patients, methods of monitoring disease progression of patients, and in diagnosing or providing a prognosis to patients having inflammato-ry or autoimmune disorders.
La présente invention concerne des profils de molécules de micro ARN et des profils de marqueurs PD induits par IFNa et IFN de type 1 dans des maladies auto-immunitaires ou inflammatoires, telles que la myosite. Les profils peuvent également être utilisés, par exemple, dans des procédés de traitement de patients, des procédés de surveillance de la progression de la maladie chez les patients, et dans le diagnostic ou létablissement dun pronostic chez des patients souffrant de maladies auto-immunitaires ou inflammatoires.
Greenberg Steven A.
Higgs Brandon
Jallal Bahija
Morehouse Chris
Yao Yihong
Brigham And Women's Hospital Inc.
Medimmune Llc
Smart & Biggar
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