G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/50 (2006.01) C12N 5/06 (2006.01)
Patent
CA 2659720
The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising a three-dimensional matrix comprising lymphoid tissue, a three-dimensional matrix comprising epithelial and/or endothelial cells, and diseased cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologies and other chemicals.
La présente invention concerne des procédés de préparation d'un système immunitaire artificiel. Le système immunitaire artificiel est constitué d'une culture cellulaire qui comporte une matrice tridimensionnelle contenant un tissu lymphoïde, une matrice tridimensionnelle contenant des cellules épithéliales et/ou endothéliales, et des cellules malades. Le système immunitaire artificiel de la présente invention peut être utilisé pour des essais in vitro de vaccins, d'adjuvants, de candidats immunothérapeutiques, de produits cosmétiques, de médicaments, de processus biologiques et autres substances chimiques.
Fahlenkamp Heather
Higbee Russell
Mishkin Eric
Rivard Michael
Sanchez-Schmitz Guzman
Fasken Martineau Dumoulin Llp
Sanofi Pasteur Vaxdesign Corp.
Vaxdesign Corp.
LandOfFree
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