Disease-resistant transgenic plants

C - Chemistry – Metallurgy – 12 – N

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195/1.2, 195/1.2

C12N 15/82 (2006.01) C07K 14/415 (2006.01) C12N 5/10 (2006.01) C12N 9/08 (2006.01) C12N 9/24 (2006.01)

Patent

CA 2012778

The present invention relates to chimeric DNA constructs useful for producing transgenic disease-resistant plants and to genetic engineering of plants to produce the phenotype of disease resistance. In particular it relates to constitutive expression in transgenic plants of DNA sequences which encode pathogenesis-related proteins (PRPs). The present invention also relates to transgenic plants constitutively expressing induced levels of plant PRPs or substantially homologous proteins, providing an enhanced disease-resistant phenotype with respect to wild-type plants. The present invention further relates to transgenic plants constitutively transcribing sense or antisense mRNA strands of DNA sequences encoding plant PRPs or transcribing sense or antisense mRNA strands of DNA sequences substantially homologous to genomic or cDNA sequences encoding plant PRPs, such transgenic plants thus having an enhanced disease- resistant phenotype with respect to wild-type plants.

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