Disinfectant/sterilant for medical devices and topical...

A - Human Necessities – 61 – L

Patent

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Details

A61L 2/00 (2006.01) A01N 37/16 (2006.01) A01N 55/08 (2006.01) A01N 59/14 (2006.01) A61K 8/22 (2006.01) A61K 8/24 (2006.01) A61K 8/37 (2006.01) A61K 8/46 (2006.01) A61L 2/16 (2006.01) A61L 2/18 (2006.01) A61L 2/23 (2006.01) A61Q 17/00 (2006.01) C11D 3/39 (2006.01)

Patent

CA 2475361

A powder composition which reacts in water to form in situ peroxycarboxylic acids at an anti-microbially effective concentration. Importantly, its utility is both for topical anti-microbial application and for effective low temperature disinfection/sterilization of instruments. It comprises the combination of a perborate, one or more novel acyl and/or aroyl donors, a buffering system which allows the pH to arise to about 9 for rapid formation of the peroxycarboxylic acids and then drop to about 7.5 for sustained stability and microbial kill. It preferably includes a surfactant facilitating antimicrobial efficacy, as well as other minors.

La présente invention concerne une poudre qui réagit dans l'eau pour former in situ des acides peroxycarboxyliques à une concentration antimicrobienne efficace. La poudre de l'invention présente une utilité importante tant pour l'application antimicrobienne locale que pour une désinfection ou stérilisation efficace d'instruments à basse température. La poudre précitée comprend une combinaison de perborate, d'un ou plusieurs nouveaux donneurs acyle et/ou aroyle, d'un système de tamponnage qui permet une augmentation du pH jusqu'à environ 9 autorisant la formation rapide des acides peroxycarboxyliques et une chute ultérieure du pH jusqu'à environ 7,5 autorisant une stabilité et une activité antimicrobienne durables. La poudre de l'invention comprend de préférence un tensio-actif facilitant l'efficacité antimicrobienne, et d'autres substances en quantité moindre.

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