A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/158, 167/244
A61K 31/35 (2006.01) A61K 9/12 (2006.01) A61K 9/72 (2006.01) A61M 11/00 (2006.01) A61M 15/00 (2006.01) B65D 83/14 (2006.01)
Patent
CA 1329362
Abstract Pharmaceutical Compositions A solutions of an inhalation medicament is packaged in a sealed dispenser containing a pressurised gas and provided with a one-way outlet valve, eg a metering valve. The dispenser may be prepared by introducing the solution and the pressurised gas into the dispenser under sterile conditions. Alternatively, the dispenser may be sterilised after introduction of the solution and gas. After being dispensed from the dispenser, the solution can be administered by nebulisation. A particularly preferred solution for use in conjunction with the dispensers contains sodium cromoglycate and chlorbutol. This solution is indicated for use in the treatment of reversible obstructive airways disease. An aqueous solution of sodium cromoglycate and chlorbutol is prepared by dissolving the chlorbutol in distilled water at a temperature of 20-60°C in a covered or sealed vessel and admixing the resulting solution with solid sodium cromoglycate.
594241
Chawla Brindra Paul Singh
Clark Andrew Reginald
Dean Desmond Alfred
Fisons Plc
Ridout & Maybee Llp
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