Dispersible antibacterial pharmaceutical compositions

Details Dispersible antibacterial pharmaceutical compositions Dispersible antibacterial pharmaceutical compositions

A - Human Necessities

61

K

A61K 47/44 (2006.01) A61K 9/00 (2006.01) A61K 31/415 (2006.01) A61K 31/43 (2006.01) A61K 31/545 (2006.01) A61K 31/65 (2006.01) A61K 45/06 (2006.01) A61K 47/06 (2006.01)

Patent

CA 2504065

A pharmaceutical composition is provided comprising a vehicle that comprises (a) an amphipathic oil that is water dispersible and ethanol insoluble, (b) microcrystalline wax, and (c) a pharmaceutically acceptable non-aqueous carrier; and having an antibacterial substance in an antibacterially effective amount stably dispersed in the vehicle. The composition is suitable for administrationby intramammary infusion to a milk producing animal for treatmen t and/or prevention of mastitis or other diseases of the udder, as well as for otic administration for treatment and/or preventionof an ear infection.

L'invention concerne une composition pharmaceutique comprenant un excipient renfermant (a) une huile amphipathique hydrodispersible et un éthanol insoluble, (b) une cire microcristalline et (c) un support non aqueux pharmaceutiquement acceptable ; et ayant une substance antibactérienne selon une quantité efficace en termes antibactériens dispersée de manière stable dans l'excipient. La composition se prête à une administration par infusion intramammaire à un animal produisant du lait en vue du traitement et/ou de la prévention de la mastite ou d'autres maladies affectant les mamelles, ainsi qu'à une administration otique en vue du traitement et/ou de la prévention d'une infection des oreilles.

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