Dispersible formulation of an anti-inflammatory agent

Details Dispersible formulation of an anti-inflammatory agent Dispersible formulation of an anti-inflammatory agent

A - Human Necessities

61

K

A61K 47/44 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2519125

A method is provided for treatment of an inflammatory condition in a fluid- containing organ having a natural exterior orifice, such as the udder of a milk producing animal or an ear. The method comprises administering, to the organ via the exterior orifice, a pharmaceutical composition comprising an anti-inflammatory agent and a vehicle that comprises an amphipathic oil that is water dispersible and ethanol insoluble, microcrystalline wax and a pharmaceutically acceptable non-aqueous carrier. Also provided is such a composition comprising the anti-inflammatory agent. The composition is readily dispersible in the fluid of the fluid-containing organ.

Selon ce procédé de traitement d'une condition inflammatoire d'un organe qui contient un fluide et est pourvu d'un orifice extérieur naturel, tel que le pis d'une bête laitière ou une oreille, on administre à l'organe, par l'orifice extérieur, une composition pharmaceutique qui contient un agent anti-inflammatoire et un excipient qui comprend une huile amphipathique dispersible dans l'eau et insoluble dans l'éthanol, une cire microcristalline et un substrat non aqueux pharmaceutiquement acceptable. L'invention concerne également une composition qui contient l'agent anti-inflammatoire. La composition se laisse aisément disperser dans le fluide contenu dans l'organe.

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