C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/58 (2006.01) A61K 31/513 (2006.01) A61K 38/46 (2006.01) A61K 38/47 (2006.01) A61K 38/48 (2006.01) A61L 15/38 (2006.01) A61L 15/46 (2006.01) A61L 27/54 (2006.01) A61L 29/16 (2006.01) A61L 31/16 (2006.01) A61P 1/02 (2006.01) A61P 17/02 (2006.01) A61P 31/00 (2006.01) B05D 1/02 (2006.01) C12N 9/00 (2006.01) C12N 9/22 (2006.01) C12N 9/24 (2006.01)
Patent
CA 2720301
The present invention provides antibiofilm composition comprising two or more agents selected from the group consisting of DispersinB.TM., 5-Fluorouracil, Deoxyribonuclease I and Proteinase K for preventing growth and proliferation of biofilm-embedded microorganisms in wound care, oral care, and disease-related infections and methods of treatment in mammals. The invention further provides methods for preparing medical devices, and wound care devices using an antibiofilm composition comprising two or more antimicrobial agents selected from the group consisting of DispersinB.TM., 5-Fluorouracil, Deoxyribonucle-ase I and Proteinase K.
La présente invention concerne une composition anti-biofilm comportant au moins deux agents choisis parmi le groupe constitué de DispersinB(MD), le 5-fluorouracile, la désoxyribonucléase I et la protéinase K pour inhiber la croissance et la prolifération de micro-organismes incorporés au biofilm dans les soins pour lésions, les soins oraux, et des infections associées à des maladies ainsi que des procédés de traitement de mammifères. L'invention concerne également des procédés de préparation de dispositifs médicaux, et des dispositifs de soins pour lésions mettant en uvre une composition anti-biofilm comportant au moins deux agents choisis parmi le groupe constitué de DispersinB(MD), le 5-fluorouracile, la désoxyribonucléase I et la protéinase K.
Gawande Purushottam
Kaplan Jeffrey B.
Lovetri Karen
Madhyastha Srinivasa
Yakandawala Nandadeva
Kane Biotech Inc.
Ridout & Maybee Llp
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