A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/10 (2006.01) A61K 47/30 (2006.01) A61K 47/44 (2006.01)
Patent
CA 2670453
The invention relates to injectable pharmaceutical compositions featuring sustained release of at least one active principle, and comprising at least one active principle in an aqueous phase of amphiphilic polymer, in disperse form in a continuous lipid phase. The composition takes the form of a water-in-oil emulsion comprising: a pharmaceutically acceptable lipid continuous phase; an aqueous disperse phase containing at least one amphiphilic polymer and at least one active principle which is not covalently bonded to said amphiphilic polymer; and at least one pharmaceutically acceptable surfactant.
L' invention concerne des composition pharmaceutique injectables, à libération prolongée d' au moins un principe actif, comprenant au moins un principe actif dans une phase aqueuse de polymère amphiphile, sous forme dispersée dans une phase lipidique continue. La composition est sous la forme d une émulsion eau-dans-l' huile comprenant: une phase continue lipidique pharmaceutiquement acceptable, une phase dispersée aqueuse contenant au moins un polymère amphiphile et au moins un principe actif non lié de façon covalente au dit polymère amphiphile, au moins un tensioactif pharmaceutiquement acceptable.
Flamel Technologies
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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