Displacement chemical regeneration method and apparatus

G - Physics – 01 – N

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G01N 30/96 (2006.01) B01D 15/10 (2006.01)

Patent

CA 2664723

One embodiment of apparatus according to the invention includes (a) a chromatographic separator, (b) a source of an aqueous eluent solution comprising electrolyte in fluid communication with the chromatographic separator, (c) a flow-through ion exchange packing suppressor, including a chromatography effluent flow channel and in fluid communication with the separator outlet, (d) a container including an inlet and an outlet, the container outlet being in fluid communication with the chromatography effluent flow channel, (e) a regenerant liquid reservoir in the container of a different chemical composition than the chromatography effluent, (f) a detector for detecting ionic species in fluid communication with the chromatography effluent flow channel, and (g) a recycle conduit for the flow of effluent from the detector to said container inlet. In another embodiment of the apparatus, the suppressor is a membrane suppressor comprising a chromatography effluent flow channel separated by an ion exchange membrane from a regenerant flow channel having an inlet and an outlet.

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