Disposable bioreactor systems and methods

C - Chemistry – Metallurgy – 12 – M

Patent

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C12M 1/00 (2006.01)

Patent

CA 2569405

Accordingly, in one embodiment of the invention, a bioreactor system is presented and includes a disposable container for housing biomaterials for processing, the disposable container including at least one input port, at least one exhaust port, at least one harvest port, and the integrity of the sterile environment is protected with sterile filters attached to all external open ports a structure for supporting the disposable container, one or more sensors for sensing one or more parameters of the biomaterials in the container, a heater for heating the contents of the container, the heater having a thermostat and mixing system arranged with the system such that biomaterials contained in the disposable container are mixed.

Dans un mode de réalisation de l'invention, un système de bioréacteur est présenté et comporte un contenant jetable destiné à abriter des biomatières à traiter. Le contenant jetable présente au moins un orifice d'entrée, au moins un orifice de sortie, au moins un orifice de traite, et l'intégrité de l'environnement stérile est protégée avec des filtres stériles fixés sur tous les orifices ouverts externes. Ledit système de bioréacteur comprend aussi une structure de support du contenant jetable, au moins un détecteur d'au moins un paramètre des biomatières du contenant, un dispositif chauffant destiné à chauffer les contenus du contenant. Ledit dispositif chauffant a un thermostat et un système de mélange conçu avec le système, de telle manière que des biomatières contenues dans le contenant jetable sont mélangées.

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