Disposable dosage unit for iontophoresis-facilitated delivery

A - Human Necessities – 61 – N

Patent

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A61N 1/30 (2006.01)

Patent

CA 2173452

Provided are disposable dosage units for use in iontophoresis facilitated delivery which have hydrophilic polymer first (28) and second (24) layers, the first layer (28) having ionic resin particles dispersed therein, and the second layer having an ionized pharmaceutical. The second layer (24) has on its surface a thin fabric layer (18) bearing an adhesive layer (20). The polymer first and second layers are separated by a permselective membrane (22). Also provided are related devices and processes using the novel disposable dosage units.

L'invention se rapporte à des unités posologiques jetables servant à faciliter par l'iontophorèse la libération transdermique de substances, ces unités étant dotées d'une première (28) et d'une seconde (24) couches polymères; la première couche (28) contient des particules de résines ioniques dispersées, et la seconde (24) contient des substances pharmaceutiques ionisées. On a déposé sur la surface de la seconde couche (24) une couche d'une étoffe fine (18) portant une couche adhésive (20). Les première et seconde couches polymères sont séparées par une membrane permsélective (22). L'invention concerne également des dispositifs et procédés apparentés utilisant ces nouvelles unités de dosage jetables.

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