Disruption of the prostaglandin e synthase 2 gene

Details Disruption of the prostaglandin e synthase 2 gene Disruption of the prostaglandin e synthase 2 gene

A - Human Necessities

01

K

A01K 67/027 (2006.01) C07K 14/775 (2006.01) C12N 5/06 (2006.01) C12N 5/10 (2006.01) C12N 9/90 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2468131

The present invention features genetically-modified non-human mammals and animal cells containing a disrupted prostaglandin E synthase 2 gene as well as methods of treating an inflammation-mediated disorder involving administering an agent that inhibits prostaglandin E synthase 2.

L'invention concerne des cellules d'animaux et de mammifères non humains génétiquement modifiées et contenant un gène dissocié de la prostaglandine E synthase-2, ainsi que des méthodes pour traiter un trouble associé à une inflammation par l'administration d'un agent inhibant la prostaglandine E synthase-2.

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