Dissolution test equipment and methods for testing

G - Physics – 01 – N

Patent

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G01N 13/00 (2006.01)

Patent

CA 2707965

Apparatus and method for testing release from a drug sample, comprising: a generally cylindrical vessel, optionally having a lower portion of the vessel in a shape of a hemisphere; a shaft and a paddle connected to the shaft suspended within the vessel, the shaft centred on the vessel; and a sample holder mounted to or suspended within the vessel and a basket mounted to the sample holder. The system is configured for circulating a medium within the vessel and around the drug sample.

L'invention porte sur un appareil et une méthode d'évaluation de la libération à partir d'un échantillon de médicament comprenant: un récipient sensiblement cylindrique dont la partie inférieure est facultativement hémisphérique; un arbre et un agitateur connectée à l'arbre, suspendus dans le récipient, l'arbre étant centré sur le récipient; un porte-échantillon monté ou suspendu dans le récipient; et un panier fixé au porte-échantillon. Le système est configuré pour faire circuler un milieu dans le récipient et autour de l'échantillon de médicament.

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