Dissolution testing apparatus calibrator

Details Dissolution testing apparatus calibrator Dissolution testing apparatus calibrator

G - Physics

01

N

G01N 11/02 (2006.01) G01N 27/416 (2006.01) G01N 27/49 (2006.01)

Patent

CA 2544385

A method is provided for probing the effective hydrodynamic flow of a liquid at various positions within a dissolution testing apparatus. The method includes embodiments of an appropriate electrode probe, and methods of generating a signature pattern from the sampled current that may be used to characterise the hydrodynamic flow of the liquid in the apparatus. The signature pattern may be used to validate and qualify the performance of the dissolution apparatuses, diagnose problems with dissolution apparatuses, predict the initial dissolution rate of a drug, or determine the local flow rate around specific parts of a drug.

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