Dissolvable oxides for biological applications

C - Chemistry – Metallurgy – 01 – B

Patent

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Details

C01B 33/16 (2006.01) A61K 9/06 (2006.01) A61K 47/02 (2006.01)

Patent

CA 2257172

The present invention is concerned with controllably dissolvable silica- xerogels prepared via sol-gel process and their use. Specifically, the invention is concerned with a delivery device comprising controllably dissolvable silica-xerogel into which structure a biologically active agent is incorporated. The invention is further concerned with pharmaceutical preparations comprising said delivery device. Further, the invention is directed to medical devices for orthopedic and surgical purposes comprising controllably dissolvable silica-xerogels, which may further comprise a biologically active agent.

La présente invention concerne des xérogels de silice solubles, de manière régulable, préparés selon un procédé sol-gel, et leur utilisation. De manière spécifique, l'invention traite d'un dispositif d'apport comprenant un xérogel de silice soluble, de manière régulable, dans lequel est incorporé un agent biologiquement actif. L'invention traite aussi de préparations pharmaceutiques comprenant ce dispositif d'apport. En outre, l'invention a pour objet des dispositifs médicaux pour des applications orthopédiques et chirurgicales comprenant des xérogels de silice solubles, de manière régulable, qui peuvent comporter, en outre, un agent biologiquement actif.

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