Disubstituted polymethylene-imines, their preparation...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/04 (2006.01) A61K 31/505 (2006.01) A61K 31/53 (2006.01) C07D 401/12 (2006.01) C07D 403/04 (2006.01)

Patent

CA 2046746

A B R E G E POLYMETHYLENE - IMINES DISUBSTITUEES, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES LES CONTENANT Nouvelles polyméthylène-imines utilisables comme médicaments, et répondant à la formule : Image dans laquelle : X, A, Z, R, R1, R2, R3, R4, Y, Y', m et n sont tels que définis dans la description. Ces nouveaux dérivés et leurs sels physiologiquement tolérables peuvent être utilisés en thérapeutique, notamment pour supprimer la résistance des cellules tumorales aux agents anti-cancéreux et pour supprimer la résistance des parasites aux agents anti-parasitaires.

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