Disubstituted proline derivatives, a process for their...

Details Disubstituted proline derivatives, a process for their... Disubstituted proline derivatives, a process for their...

C - Chemistry, Metallurgy

07

D

260/316, 260/557

C07D 209/02 (2006.01) C07D 207/16 (2006.01) C07D 209/42 (2006.01) C07D 209/52 (2006.01) C07F 3/10 (2006.01)

Patent

CA 1220213

ABSTRACT OF THE DISCLOSURE The invention relates to compounds of the formula I Image (I) in which R1 and R2 are identical or different and represent straight-chain or branched alkyl having 1 to 6 carbon atoms or represent (C6 to C10)-aryl, preferably phenyl, or together represent one of the chains -(CH2)n- or -(CH2)p-CH=CH-(CH2)q, n, p and q each being an integer, n being 3-6 and (p+q) being 1-4, and R3 denotes straight-chain or branched alkyl having 1 to 5 carbon atoms or (C6 to C10)-aryl, preferably phenyl, and a process for their preparation and their use. Compounds of the formula I are useful intermediates for the preparation of inhibitors of the angiotension converting enzyme (ACE).

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