Disubstituted proline derivatives, a process for their...

Details Disubstituted proline derivatives, a process for their... Disubstituted proline derivatives, a process for their...

C - Chemistry, Metallurgy

07

D

260/317, 260/323

C07D 207/16 (2006.01) C07D 209/02 (2006.01)

Patent

CA 1235128

ABSTRACT OF THE DISCLOSURE The invention relates to compounds of the formula IV Image (IV) in which R1 and R2 are identical or different and represent straight-chain or branched alkyl having 1 to 6 carbon atoms or represent (C6 to C10)-aryl, or together represent one of the chains -(CH2)n- or -(CH2)p-CH=CH-(CH2)q, n, p and q each being an integrer, n being 3-6 and (p+q) being 1-4, and R represents hydrogen, alkyl having 1 to 10 carbon atoms, aralkyl having 7 to 9 carbon atoms, cycloalkyl having 5 to 10 carbon atoms, alkylcycloalkyl having 6 to 12 carbon atoms or cycloalkylalkyl having 6 to 12 carbon atoms, and to processes for their preparation. Compounds of the formula IV are useful intermediates in the production of inhibitors of the angiotension converting enzyme (ACE).

511617

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