Disulfide core polypeptides

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/15 (2006.01) C07K 14/81 (2006.01) C07K 16/38 (2006.01) C07K 16/42 (2006.01)

Patent

CA 2330187

The present invention relates to polynucleotide and polypeptide molecules for a disulfide core protein (Zdsc1). The polypeptides, and polynucleotides encoding them, are serine proteinase inhibitors. Also disclosed are expression vectors containing polynucleotides which encode a Zdsc1 polypeptide, antibodies which specifically bind to Zdsc1 polypeptides and anti-idiotypic antibodies which neutralize the antibodies which specifically bind to Zdsc1 polypeptides.

La présente invention concerne des molécules de polynucléotides et de polypeptides (Zdsc1). Les polypeptides, et les polynucléotides codant pour ces polypeptides, sont des inhibiteurs de la sérine protéinase. L'invention concerne également des vecteurs d'expression renfermant des polynucléotides qui codent pour un polypeptide Zdsc1, des anticorps qui se lient spécifiquement à des polypeptides Zdsc1 et des anticorps anti-idiotypiques neutralisant les anticorps que se lient spécifiquement aux polypeptides Zdsc1.

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