Disulfide cross-linking glycoprotein hormone analogs, and...

Details Disulfide cross-linking glycoprotein hormone analogs, and... Disulfide cross-linking glycoprotein hormone analogs, and...

C - Chemistry, Metallurgy

12

N

C12N 15/16 (2006.01) A61K 38/24 (2006.01) C07K 14/00 (2006.01) C07K 14/59 (2006.01) C12N 5/10 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2293731

The invention relates to analogs of glycoprotein hormones with an intersubunit disulfide cross-link and their preparation and use. Corresponding DNA sequences and host cells, as well as pharmaceutical compositions are also disclosed.

L'invention concerne des analogues d'hormones glycoprotéiques dotées d'une liaison réticulée disulfite entre sous-unités, leur préparation et leur utilisation. L'invention se rapporte également à des séquences d'ADN et à des cellules hôtes correspondantes ainsi qu'à des compositions pharmaceutiques.

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