Disulfide derivatives useful for treating allergic diseases

Details Disulfide derivatives useful for treating allergic diseases Disulfide derivatives useful for treating allergic diseases

C - Chemistry, Metallurgy

07

C

C07C 323/44 (2006.01) A61K 31/17 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2407964

Diphenyl disulfide derivatives of formula (I) wherein X is -NHC(=O)NH-R and R is as defined in the claims are useful for preventing or treating allergic diseases of the eye, nose, skin, ear, gastrointestinal tract, airways or lung and preventing or treating manifestations of systemic mastocytosis. The disulfide derivatives act as mast cell stabilizers.

L'invention concerne des dérivés de bisulfure de diphényle de formule (I) dans laquelle X représente -NHC(=O)NH-R et R est défini comme dans les revendications, lesdits dérivés étant utilisés dans la prévention ou le traitement de maladies allergiques affectant les yeux, le nez, la peau, les oreilles, le tractus gastro-intestinal, les voies aériennes ou les poumons, et dans la prévention ou le traitement de manifestations de mastocytose systémique. Les dérivés de bisulfure agissent comme des stabilisants de mastocytes.

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