C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/06 (2006.01) A61K 31/21 (2006.01) A61K 31/395 (2006.01) A61K 38/04 (2006.01) C07C 323/59 (2006.01) C07C 323/60 (2006.01) C07D 295/185 (2006.01)
Patent
CA 2165992
Compounds of the general formula (I): (see formula I) in which R and R' denote groups of the general formulae (see formula II) and the physiologically tolerated salts thereof. Those compounds are usefull for the treatment of heast diseases and display no nitrate tolerance on continuing intake. Process for the preparation of the compounds of the general formula (I).
La présente invention concerne de nouveaux nitrates contenant un groupe disulfure, par exemple de la formule (I), dans laquelle R, R', R<1>, R<1'>, R<2>, R<2'>, R<3>, R<3'>, R<4>, R<4'>, R<5>, R<5'>, m, m', n, n', o, o', p, p', q, q' sont tels qu'ils sont définis dans la revendication 1, et des procédés pour leur fabrication. Les composés peuvent être utilisés pour le traitement de maladies du système cardio-vasculaire.
Bokens Hilmar
Feelisch Martin
Lehmann Jochen
Meese Claus
Sandrock Klaus
Robic
Schwarz Pharma Ag
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