Diterpenoid compounds, compositions thereof and their use as...

C - Chemistry – Metallurgy – 07 – C

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Details

C07C 43/162 (2006.01) A61K 31/085 (2006.01) A61K 31/121 (2006.01) A61K 31/502 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01) C07C 43/164 (2006.01) C07C 45/29 (2006.01) C07C 49/115 (2006.01) C07C 49/12 (2006.01) C07C 49/225 (2006.01) C07C 49/755 (2006.01) C07C 69/00 (2006.01)

Patent

CA 2508002

The present invention relates to Diterpenoid Compounds, compositions comprising an effective amount of a Diterpenoid Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering an effective amount of a Diterpenoid Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, or for inducing apoptosis in a cancer or neoplastic cell. The compounds, compositions, and methods of the invention are further useful for treating or preventing a fungal infection. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a fungus.

La présente invention porte sur des composés diterpénoïdes, sur des compositions contenant une quantité efficace d'un composé diterpénoïde, ainsi que sur des méthodes permettant de traiter ou de prévenir le cancer ou un trouble néoplasique et consistant à administrer une quantité efficace d'un composé diterpénoïde. Les composés, compositions et méthodes de cette invention permettent également d'inhiber la croissance d'une cellule cancéreuse ou d'une cellule néoplasique et à induire l'apoptose dans une cellule cancéreuse ou néoplasique. Les composés, compositions et méthodes de cette invention permettent en outre de traiter ou de prévenir les infections fongiques. Les composés, compositions et méthodes de cette invention permettent enfin d'inhiber la croissance d'un champignon.

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