Dithienofuran dyes for imaging and therapy

Details Dithienofuran dyes for imaging and therapy Dithienofuran dyes for imaging and therapy

A - Human Necessities

61

K

A61K 49/00 (2006.01) A61K 41/00 (2006.01) C09K 11/06 (2006.01) C07D 495/14 (2006.01)

Patent

CA 2737915

The invention provides optical agents, including compositions, preparations and formulations, and methods of using and making optical agents. Optical agents of the present invention include dyes, and derivatives thereof, having a fused ring backbone structure having dithienofuran core. In some embodiments, dyes of the present invention are dithienofuran dyes having a dithienofuran core optionally functionalized to provide useful optical, biological, pharmacokinetic and/or physical properties.

La présente invention concerne des agents optiques comprenant des compositions, des préparations et des formulations, ainsi que des procédés d'utilisation et de préparation de ces agents optiques. Les agents optiques selon la présente invention comprennent des colorants et des dérivés de ces derniers qui ont une structure de squelette à cycles fusionnés ayant un noyau dithiénofurane. Dans certains modes de réalisation, les colorants selon la présente invention sont des colorants au dithiénofurane ayant un noyau dithiénofurane facultativement fonctionnalisé pour assurer des propriétés optiques, biologiques, pharmacocinétiques et/ou physiques utiles.

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