Dithienopyrrole dyes for imaging and therapy

Details Dithienopyrrole dyes for imaging and therapy Dithienopyrrole dyes for imaging and therapy

A - Human Necessities

61

K

A61K 49/00 (2006.01) A61K 41/00 (2006.01) C09K 11/06 (2006.01) C07D 495/14 (2006.01)

Patent

CA 2738035

The invention provides optical agents, including compositions, preparations and formulations, and methods of using and making optical agents. Optical agents of the present invention include dyes, and derivatives thereof, having a fused ring backbone structure having dithienopyrrole core. In some embodiments, dyes of the present invention are dithienopyrrole dyes having a dithienopyrrole core optionally functionalized to provide useful optical, biological, pharmacokinetic and/or physical properties.

La présente invention concerne des agents optiques, y compris des compositions, des préparations et des formulations, ainsi que des procédés d'utilisation et de production des agents optiques. Les agents optiques selon la présente invention comprennent des colorants et des dérivés de ces derniers, qui ont une structure de squelette à anneaux fusionnés ayant un noyau dithiénopyrrole. Dans certains modes de réalisation, les colorants selon l'invention sont des colorants au dithiénopyrrole ayant un noyau dithiénopyrrole éventuellement fonctionnalisé pour présenter des propriétés optiques, biologiques, pharmacocinétiques et/ou physiques utiles.

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