Dithiolopyrrolone derivatives useful in the treatment of...

C - Chemistry – Metallurgy – 07 – D

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C07D 495/04 (2006.01) A61K 31/407 (2006.01) A61P 35/00 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2479341

The present invention provides novel dithiolopyrrolone compounds of Formula (I) and their salts, which are useful as treatment for cancer and other proliferative diseases. The present invention also provides therapeutic compositions comprising particularly useful types of dithiolopyrrolones, the salts thereof, and methods of using the compounds within such types, particularly in treating proliferative diseases such as cancer.

Cette invention à trait à de nouveaux composés de dithiolopyrrolone et à leurs sels, se révélant des plus utiles en matière de traitement du cancer et d'autres maladies prolifératives. Elle concerne également des compositions thérapeutiques contenant certains types de dithiolopyrrolones particulièrement utiles ainsi que leurs sels. Elle porte, de surcroît, sur des méthodes d'utilisation de ces composés, notamment pour le traitement de maladies prolifératives telles que le cancer.

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