Diuretic and natriuretic polypeptides

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/46 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2660294

This document provides diuretic and natriuretic polypeptides. For example, this document provides polypeptides having diuretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have diuretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing diuretic and/or natriuretic activities within a mammal.

La présente invention concerne des polypeptides diurétiques et natriurétiques. Par exemple, la présente invention concerne des polypeptides ayant des activités diurétiques et/ou natriurétiques. Dans certains cas, un polypeptide selon la présente invention peut avoir des activités diurétiques et natriurétiques, tout en étant exempt de la capacité d'abaisser la pression artérielle. La présente invention concerne également des procédés et des matériaux pour induire des activités diurétiques et/ou natriurétiques chez un mammifère.

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