Diuretic composition containing furosemide

Details Diuretic composition containing furosemide Diuretic composition containing furosemide

A - Human Necessities

61

K

167/102

A61K 9/36 (2006.01) A61K 9/50 (2006.01) A61K 31/635 (2006.01)

Patent

CA 1292684

27243-27 ABSTRACT OF THE DISCLOSURE The present invention relates to a multiple-unit dose com- position comprising furosemide as pharmaceutically active compound, whereby the composition gives a release of furosemide in accordance with Dissotest in a buffer having pH 1.5 of at most 4% during hour 1, a release in a buffer having pH 5.5 of at most 7.5% during a con- secutive hour (hour 2), a release of furosemide in a buffer having pH 7.5 of at least 65% during a further consecutive hour (hour 3), and a release of furosemide in a buffer having pH 7.5 of at least 90% during a consecutive hour (hour 4).

556485

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