C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
530/13, 195/1.2,
C12N 15/16 (2006.01) A61K 38/22 (2006.01) C07K 14/58 (2006.01) C12N 15/73 (2006.01) A61K 38/00 (2006.01)
Patent
CA 1340454
A DNA fragment including a base sequence coding for a peptide occurring in rat atrium cordis and having diuretic action or a precursor of the peptide, plasmids containing the DNA fragment, microorganisms transformed with the plasmid, and a process for production of the peptide using the transformant. A new peptide consisting of 126 amino acids occurring in rat atrium cordis and a precursor thereof. The peptide has notable diuretic action and hypotensive or antihypertensive actions.
484866
Hayashi Yujiro
Kangawa Kenji
Matsuo Hisayuki
Nakazato Hiroshi
Oikawa Shinzo
Hayashi Yujiro
Kangawa Kenji
Matsuo Hisayuki
Nakazato Hiroshi
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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