Divisible tablet with delayed release of active substance...

Details Divisible tablet with delayed release of active substance... Divisible tablet with delayed release of active substance...

A - Human Necessities

61

K

167/166

A61K 47/00 (2006.01) A61K 9/20 (2006.01) A61K 9/26 (2006.01) A61K 31/415 (2006.01) A61K 9/14 (2006.01)

Patent

CA 1232202

ABSTRACT The invention relates to a divisible polyacrylate-based tablet with delayed release of the active substance which consists of a pressed blank of finely divided polyacrylate material with conventional tablet-making excipients and the active substance incorporated as a molecular dispersion in the polymer. In order to produce the divisible tablet, the pharmaceutical active substance together with the polyacrylate is dissolved in an organic solvent, the solvent is evaporated off, the solid active substance- containing polyacrylate is ground at a temperature below the glass temperature, the active substance-containing polyacrylate powder is processed with conventional tablet-making excipients and compressed to form tablets.

452163

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