Dkk-1 antibodies

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/18 (2006.01)

Patent

CA 2758252

The invention provides human engineered antibodies, antigen-binding fragments thereof, that bind to, and inhibit the activity of, human DKK-1, and which are effective in treating diseases in which pathogenesis is mediated by DKK-1.

La présente invention concerne des anticorps humains modifiés et des fragments de liaison d'antigène de ceux-ci, qui se lient à, et inhibent l'activité de, DKK-1 humain, et qui sont efficaces dans le traitement de maladies dans lesquelles la pathogenèse est médiée par DKK-1.

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