C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/18 (2006.01)
Patent
CA 2758252
The invention provides human engineered antibodies, antigen-binding fragments thereof, that bind to, and inhibit the activity of, human DKK-1, and which are effective in treating diseases in which pathogenesis is mediated by DKK-1.
La présente invention concerne des anticorps humains modifiés et des fragments de liaison d'antigène de ceux-ci, qui se lient à, et inhibent l'activité de, DKK-1 humain, et qui sont efficaces dans le traitement de maladies dans lesquelles la pathogenèse est médiée par DKK-1.
Chedid Marcio
Darling Ryan James
Galvin Rachelle Jeanette
Swanson Barbara Anne
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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