Dna binding peptide domains and a method for providing such...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/11 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/00 (2006.01) C07K 14/395 (2006.01) C07K 14/47 (2006.01) C12N 15/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2420251

The invention relates to peptidic domains, which are made available in a slightly synthetic manner, and which can specifically identify and bind nucleic acid sequences. The invention also relates to a method for discovering and providing specifically DNA-binding peptide domains, and to biomorph factors derived therefrom, in particular, transcription factors and repressors.

L'invention concerne des domaines peptidiques aisément accessibles de manière synthétique, qui reconnaissent spécifiquement et lient des séquences d'acide nucléique. L'invention concerne en outre un procédé permettant de détecter et de préparer des domaines peptidiques liant l'ADN de manière spécifique, ainsi que des facteurs biomorphes qui en sont dérivés, notamment des facteurs de transcription et des répresseurs.

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