Dna coding for enzyme

Details Dna coding for enzyme Dna coding for enzyme

C - Chemistry, Metallurgy

12

N

C12N 15/57 (2006.01) C12N 1/21 (2006.01) C12N 9/52 (2006.01) C12N 9/64 (2006.01) C12P 21/00 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2074401

4-18730/A/CGJ54 DNA CODING FOR ENZYME ABSTRACT OF THE DISCLOSURE The invention concerns DNA encoding prolylendopeptidase, hybrid vectors containing such DNA, transformed hosts capable of expressing prolylendopeptidase, a process for the production of prolylendopeptidase comprising the steps of: culturing a host organism transformed with an expression vector comprising a DNA coding for prolylendopeptidase and optionally, recovering the produced prolylendopeptidase; and a process for the production of a C-terminal amidated peptide from two precursors thereof, comprising the steps of: placing the two precursors in contact with a prolylendopeptidase in a medium to convert the precursor peptides to the C-terminal amidated peptide, and recovering the resulting C-terminal amidated peptide.

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