C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 14/745 (2006.01) C07K 14/755 (2006.01) C12N 9/64 (2006.01) C12N 15/67 (2006.01) C12N 15/85 (2006.01) C12P 21/02 (2006.01)
Patent
CA 2304376
A DNA-construct has been disclosed which is suitable for a tissue-specific expression of a blood coagulation factor like Factor IX, which comprises a DNA coding for an amino acid sequence of a blood coagulation factor and a DNA coding for a promoter which is specific for the expression in hematopoietic cells.
Une construction à base d'ADN est divulguée dans la présente invention. Cette construction est destinée à l'expression dans un tissu donné d'un facteur de coagulation sanguine, par exemple le facteur IX. Elle est constituée d'un ADN codant la séquence des acides aminés d'un facteur de coagulation et d'un ADN codant un promoteur, propre à une expression dans les cellules hématopoïétiques.
Enjolras Nathalie
Negrier Claude
Rodriguez Marie Helene
Aventis Behring Gmbh
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Csl Behring Gmbh
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