Dna delivery with gemini cationic surfactants

A - Human Necessities – 61 – K

Patent

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Details

A61K 48/00 (2006.01) A61K 9/06 (2006.01) A61K 31/7088 (2006.01) A61K 38/21 (2006.01) A61K 47/44 (2006.01) A61P 17/00 (2006.01)

Patent

CA 2542708

The invention provides a delivery system for a biologically active agent comprising a gemini surfactant in admixture with the biologically active agent in a topical formulation for treatment of skin disorders or metabolic diseases. The invention also provides pharmaceutical compositions in topical formulations comprising the delivery system as set out above, in admixture with pharmaceutically acceptable carriers, diluents, excipients, or supplements suitable for application to the skin or mucosal membrane. Methods of preparation and use are also described.

L'invention concerne un système d'apport d'agent biologiquement actif, qui comprend un tensioactif géminé mélangé audit agent dans une formulation topique destinée à traiter des affections de la peau ou des maladies métaboliques. L'invention concerne aussi des compositions pharmaceutiques en formulations topiques, qui comprennent le système d'apport décrit, mélangé à des supports, diluants, excipients ou suppléments pharmaceutiquement acceptables convenant en vue d'une application sur la peau ou sur une membrane muqueuse. Des procédés de préparation et d'utilisation sont également décrits.

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