Dna demethylase, therapeutic and diagnostic uses thereof

Details Dna demethylase, therapeutic and diagnostic uses thereof Dna demethylase, therapeutic and diagnostic uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/52 (2006.01) A61K 38/43 (2006.01) A61K 48/00 (2006.01) C07K 16/40 (2006.01) C12N 9/00 (2006.01) C12N 9/10 (2006.01) C12N 15/11 (2006.01) C12N 15/81 (2006.01) C12P 7/44 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2309361

The present invention relates to a DNA demethylase enzyme having about 40 KDa, and wherein said DNA demethylase enzyme is overexpressed in cancer cells and not in normal cells. The present invention also relates to the therapeutic and diagnostic uses of the DNA demethylase.

La présente invention a trait à une enzyme, l'ADN déméthylase, d'environ 40 KDa, ladite ADN déméthylase étant surexprimée dans des cellules cancéreuses, et non dans des cellules normales. La présente invention a également trait à des utilisations thérapeutiques et diagnostiques de l'ADN déméthylase.

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