Dna encoding a human betaine/gaba transporter and uses thereof

Details Dna encoding a human betaine/gaba transporter and uses thereof Dna encoding a human betaine/gaba transporter and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/48 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2153046

This invention provides an isolated nucleic acid encoding a mammalian betaine/GABA transporter, an isolated mammalian betaine/GABA transporter, antibodies directed to the transporter, nucleic acid probes and transgenic animals. The invention further provides methods for determining substrate binding, detecting expression, drug screening and methods of treating abnormalities associated with mammalian betaine/GABA transporters.

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