Dna encoding a plasminogen activating protein

Details Dna encoding a plasminogen activating protein Dna encoding a plasminogen activating protein

C - Chemistry, Metallurgy

12

N

C12N 15/58 (2006.01) A61K 39/09 (2006.01) A61K 39/116 (2006.01) A61K 39/295 (2006.01) A61K 39/385 (2006.01) C07H 21/00 (2006.01) C07K 14/315 (2006.01) C07K 16/40 (2006.01) C12N 9/70 (2006.01) C12N 9/96 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01) G01N 33/573 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2235471

The present invention provides polynucleotide molecules comprising nucleotide sequences encoding plasminogen activating (PauA) proteins from Streptococcus uberis, and substantially homologous polypeptides, peptide fragments, and fusion proteins thereof. The present invention further provides compositions and methods for recombinantly expressing the PauA proteins, substantially homologous polypeptides, peptide fragments and fusion proteins encoded by the polynucleotide molecules of the present invention. The present invention further provides a vaccine for protecting a member of a mammalian species against mastitis, comprising a PauA protein, substantially homologous polypeptide, peptide fragment, fusion protein, or polynucleotide molecule of the present invention.

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