C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07H 21/04 (2006.01) C07K 14/755 (2006.01) C12N 5/00 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2357758
The complete sequence of the canine von Willebrand Factor cDNA and deduced amino acid sequence is provided. The mutation which causes von Willebrand's Disease in Scottish Terriers, Doberman pinschers, Shetland sheepdogs, Manchester terriers and Poodles are also provided. Methods for detecting carriers of the defective vWF gene are also provided.
L'invention concerne la séquence complète de l'ADNc du facteur Willebrand canin et la séquence d'acides aminés déduite. La mutation provoquant la maladie de Willebrand chez les scottish-terriers, les doberman-pinschers, les bergers shetland, les terriers de Manchester et les caniches est également décrite. L'invention a également trait à des méthodes de détection de vecteurs du gène WF défectif.
Brewer George J.
Schall William D.
Venta Patrick J.
Yuzbasiyan-Gurkan Vilma
Borden Ladner Gervais Llp
The Board Of Trustees Operating Michigan State University
The Regents Of The University Of Michigan
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