Dna encoding precursor interleukin 1.beta. converting enzyme

Details Dna encoding precursor interleukin 1.beta. converting enzyme Dna encoding precursor interleukin 1.beta. converting enzyme

C - Chemistry, Metallurgy

12

N

C12N 15/57 (2006.01) C12N 1/21 (2006.01) C12N 9/64 (2006.01) C12N 15/63 (2006.01) C12P 21/08 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2136981

2136981 9400154 PCTABS00030 Complementary DNA (cDNA) encoding the precursor interleukin-1.beta. (pre-IL-1.beta.) converting enzyme (ICE) is isolated from a cDNA library. A cDNA, encoding the full-length open reading frame (ORF) for the nascent ICE, as well as individual cDNAs encoding the 20 kDa subunit and the 10 kDa subunit of ICE are identified and sequenced. ICE is useful in the conversion of pre-IL-1.beta. into mature IL-1.beta.. The recombinantly produced ICE, including the individual 20 kDa and 10 kDa subunits is useful in the diagnosis of inflammatory diseases, in the production of recombinant IL-1.beta., and to identify inhibitors of ICE activity.

Affiliated with

Also associated with

Rating

Dna encoding precursor interleukin 1.beta. converting enzyme does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Dna encoding precursor interleukin 1.beta. converting enzyme, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dna encoding precursor interleukin 1.beta. converting enzyme will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1417942