Dna fragment encoding tumor cell growth inhibitors

Details Dna fragment encoding tumor cell growth inhibitors Dna fragment encoding tumor cell growth inhibitors

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 14/52 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2124941

DNA fragments encoding a tumor cell growth inhibitors and having a nucleotide sequence shown by formula (1) below, which are produced by preparing cDNA library from mRNA of the established 3T3 cell-derived cell line, amplifying various DNA fragments considered to encode the tumor cell growth inhibitors by the PCR method, analyzing the nucleotide sequences of these DNA fragments and determining the nucleotide sequences of the DNA fragments encoding the inhibitors: 27 GTG CAG ATT ACA AAG TGT AGT TCT GAC ATG GAC GGC TAC TGC 54 81 TTG CAT GGC CAG TGC ATC TAC CTG GTG GAC ATG AGA GAG AAA 108 TTC TGC AGA TGT GAA GTG GGC TAC ACT GGT CTG CGA TGT GAG CAC X ........... (1) wherein X represents TTC TTT CTA or TTC.

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