C - Chemistry – Metallurgy – 40 – B
Patent
C - Chemistry, Metallurgy
40
B
C40B 40/06 (2006.01) G06F 19/20 (2011.01) C12Q 1/68 (2006.01) C40B 30/04 (2006.01) C12P 19/34 (2006.01)
Patent
CA 2704625
Methods for detecting and mapping chromosomal rearrangements associated with various diseases using comparative genomic hybridization are disclosed. Included are methods to identify translocation partners of known genomic loci and to determine translocation breakpoints. These methods may be used in the prognosis, diagnosis, and determination of predisposition to diseases that involve chromosomal rearrangements.
La présente invention porte sur des procédés de détection et de mappage de réarrangements chromosomiques associés à diverses maladies à l'aide d'une hybridation génomique comparative. L'invention porte sur des procédés pour identifier des partenaires de translocation de loci génomiques connus et pour déterminer des points de cassure de translocation. Les procédés de la présente invention peuvent également être utilisés dans le pronostic, le diagnostic et la détermination d'une prédisposition à des maladies qui mettent en jeu des réagencements chromosomiques tels que des translocations.
Fetherstonhaugh & Co.
University Of Washington
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