C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07H 19/00 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C12M 1/00 (2006.01) C12M 1/34 (2006.01) C12N 15/09 (2006.01) C12P 19/34 (2006.01)
Patent
CA 2460679
Methods are disclosed for the construction of and interrogation of DNA arrays containing Active Chromatin Elements, and, thereby active genetic regulatory sequences.. Further methods are disclosed for interrogation of such arrays in order to reveal the pattern of genetic regulatory activity within any given cell or tissue type under a variety of conditions.
L'invention a trait à des procédés permettant la construction et l'interrogation de puces à ADN contenant des éléments de chromatine active, et donc des séquences de régulation génique actives. L'invention concerne également des procédés permettant d'interroger de telles puces à ADN, afin de mettre en évidence le profil de l'activité de régulation génique ayant lieu à l'intérieur de tout type donné de cellule ou de tissu dans des conditions variées.
Mcarthur Michael
Stamatoyannopoulos John A.
Mcarthur Michael
Osler Hoskin & Harcourt Llp
Regulome Corporation
Stamatoyannopoulos John A.
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