C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/435 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12N 15/10 (2006.01) C12N 15/63 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2314434
The present invention discloses the isolation and characterization of cDNA molecules encoding a novel member to the human nuclear receptor superfamily, designated nNR5. Also within the scope of the disclosure are recombinant vectors, recombinant host cells, methods of screening for modulators of nNR5 activity, and production of antibodies against nNR5, or epitopes thereof.
La présente invention concerne l'isolement et la caractérisation de molécules d'ADNc codant un nouveau membre de la superfamille des récepteurs nucléaires humains, à savoir nNR5. L'invention concerne également des vecteurs recombinés, des cellules hôtes recombinées, des méthodes de criblage de modulateurs de l'activité de nNR5, et la production d'anticorps contre nNR5, ou d'épitopes de ces anticorps.
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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