C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07H 21/04 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2301554
The present invention discloses the isolation and characterization of cDNA molecules encoding two human nuclear receptor proteins, designated nNR1, nNR2 and/or nNR2-1. Also within the scope of the disclosure are recombinant vectors, recombinant host cells, methods of screening for modulators of nNR1, nNR2 and/or nNR2-1 activity, and production of antibodies against nNR1, nNR2 and/or nNR2-1, or epitopes thereof.
L'invention concerne l'isolement et la caractérisation de molécules d'ADNc codant pour deux protéines réceptrices nucléaires humaines, désignées par nNR1, nNR2 et/ou nNR2-1. L'invention concerne également des vecteurs recombinants, des cellules hôtes recombinantes, des techniques de criblage permettant l'identification de modulateurs de l'activité nNR1, nNR2 et/ou nNR2-1, et la production d'antibiotiques contre nNR1, nNR2 et/ou de nNR2-1, ou des épitopes de ces derniers.
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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