C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/51 (2006.01) A61K 39/29 (2006.01) A61K 39/42 (2006.01) C07H 21/04 (2006.01) C07K 4/02 (2006.01) C07K 7/06 (2006.01) C07K 14/085 (2006.01) C07K 14/18 (2006.01) C12P 21/08 (2006.01) C12Q 1/70 (2006.01) G01N 33/576 (2006.01) G01N 33/577 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2124027
ABSTRACT OF THE DISCLOSURE The present invention provides DNAs originating in non-A non-B hepatitis virus genome gene and polypeptides constituting said virus, which enable the diagnosis of hepatitis induced by said virus. An RNA is extracted and purified from the plasma of a patient with non-A non-B hepatitis. By using this RNA as a template, a single strand DNA is prepared. Then, the DNA is amplified by the PCR method with the use of appropriately selected primers. The partial DNA sequence of the above-mentioned virus is identified by analyzing the structure and the constituting polypeptide of this virus is deduced. Thus, the antigen site is confirmed.
Aoyama Muneo
Arima Terukatsu
Hosoda Tetsuya
Iwasaki Yoshihiro
Obara Takashi
Arima Terukatsu
G. Ronald Bell & Associates
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