C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/02 (2006.01) A61K 47/12 (2006.01) A61K 48/00 (2006.01) A61K 47/02 (2006.01) A61K 47/18 (2006.01)
Patent
CA 2315032
The present invention relates to nucleic acid formulations of pharmaceutical products which comprise citrate and/or triethanolamine in concentrations which enhance stability of the nucleic acid. These formulations are suited for situations where prolonged storage occurs during the distribution and/or storage period prior to use.
La présente invention se rapporte à des formulations, à base d'acide nucléique, de produits pharmaceutiques comportant du citrate ou de la triéthanolamine à des concentrations permettant d'accroître la stabilité de l'acide nucléique. Ces formulations conviennent aux situations de stockage prolongé pouvant se produire lors de la période de distribution et/ou de stockage avant utilisation.
Bruner Mark W.
Evans Robert K.
Volkin David B.
Xu Zheng
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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